Therapsids were widely distributed in Pangea in the late Permian. South Africa in Gondwana and Russia in Laurasia are the principal areas recording tetrapods (including therapsids) of this age. More recent field explorations have increased the importance of Chinese late Permian fossil assemblages. This is clearly reflected in the discovery of several new therocephalians from the Naobaogou Formation in Nei Mongol. Here, we report a therocephalian from that unit identified as a new species of the emblematic South African taxon Euchambersia. The new species, Euchambersia liuyudongi, is represented by a well-preserved skull and mandible showing a well-developed maxillary fossa and the absence of postcanine teeth. This is the third akidnognathid therocephalian recovered from the Naobaougou Formation, but oddly, the two basal Chinese akidnognathids previously known were recovered from a younger unit of the formation than the derived E. liuyudongi. This is the first time that the same therocephalian genus has been recorded in northern and southern continents, making the record of the Naobaougou Formation key to understanding the evolution of late Permian continental fauna in general, and of akidnognathid therocephalians in particular.